Detalhe da pesquisa
1.
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.
Cell
; 151(6): 1308-18, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217712
2.
HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease.
Subcell Biochem
; 101: 389-425, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36520314
3.
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Mol Cell
; 53(2): 317-29, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462205
4.
Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
EMBO J
; 36(24): 3650-3665, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29127155
5.
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions.
Chemistry
; 26(43): 9459-9465, 2020 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32167602
6.
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
Mol Cell
; 47(3): 434-43, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22727666
7.
The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.
Hum Mol Genet
; 26(22): 4465-4480, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973376
8.
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.
Mol Cell
; 41(6): 672-81, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21419342
9.
In vivo bioassay to test the pathogenicity of missense human AIP variants.
J Med Genet
; 55(8): 522-529, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632148
10.
Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism.
Nat Chem Biol
; 12(8): 628-35, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27322067
11.
Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors.
Mol Cell
; 39(2): 269-81, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20670895
12.
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Mol Cell
; 37(3): 333-43, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159553
13.
Advances on the Structure of the R2TP/Prefoldin-like Complex.
Adv Exp Med Biol
; 1106: 73-83, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484153
14.
Mechanisms of Hsp90 regulation.
Biochem J
; 473(16): 2439-52, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27515256
15.
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.
Mol Cell
; 31(6): 886-95, 2008 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18922470
16.
Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 5): 1197-206, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25945584
17.
The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.
Hum Mol Genet
; 27(7): 1309, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351602
18.
ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.
Nat Chem Biol
; 9(5): 307-12, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23502424
19.
Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity.
Proc Natl Acad Sci U S A
; 109(8): 2937-42, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22315411
20.
Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90.
Org Biomol Chem
; 12(8): 1328-40, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24435512